Glossary
15 markers
7 test panels covered
Gut microbiome marker glossary
Every marker that shows up on a GI-MAP, Genova GI-Effects, Biomesight, or Doctor's Data report — explained in plain English. Click any marker to see what it means, what causes it, and the foods that move it.
Bacteria 6
The dominant residents of your gut. Imbalances drive most of the symptoms people walk in with.
Low
Akkermansia muciniphila
Akkermansia muciniphila is a Gram-negative, oval-shaped, anaerobic bacterium that lives in the mucus layer lining your colon.
See protocol
Low
Bifidobacterium spp.
Bifidobacterium is a genus of Gram-positive, anaerobic bacteria that dominates the infant gut (especially in breastfed infants, where it can exceed 80 percent of total bacteria) a…
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Low
Faecalibacterium prausnitzii
Faecalibacterium prausnitzii is one of the single most abundant bacteria in a healthy human colon, typically 5 to 15 percent of total gut bacteria, and one of the most important.
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Positive
H. pylori CagA
CagA (cytotoxin-associated gene A) is one of the most clinically important H.
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Positive
Helicobacter pylori
Helicobacter pylori is a spiral-shaped, microaerophilic bacterium that colonizes the lining of the human stomach.
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Low
Lactobacillus spp.
Lactobacillus is a genus of lactic acid-producing bacteria that lives throughout the human GI tract, vaginal tract, and oral cavity.
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Archaea 1
A separate domain of life, not bacteria. The methane producers behind constipation-predominant SIBO.
Fungi 1
Yeasts that live as commensals in small numbers. The clinical concern is overgrowth, usually post-antibiotic.
Parasites & protozoa 1
Almost always require clinical treatment. Dietary protocols support eradication, they do not replace it.
Host markers 6
Inflammation, immunity, and digestion markers your own body produces. Often the most actionable findings.
Elevated
Bacteroidetes/Firmicutes Ratio
The Bacteroidetes-to-Firmicutes ratio (B/F or F/B ratio, depending on which is in the numerator) compares the two largest bacterial phyla in the human gut.
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Low
Butyrate (n-Butyrate)
N-butyrate is the most studied of the short-chain fatty acids and the most important for colon health specifically.
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Elevated
Calprotectin
Calprotectin is a protein released by neutrophils (a type of white blood cell) when they migrate into the gut wall to fight inflammation.
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Low
Secretory IgA
Secretory IgA (sIgA) is your gut's primary antibody.
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Low
Total Short-Chain Fatty Acids
Short-chain fatty acids (SCFAs), primarily butyrate, propionate, and acetate, are the end products when your gut bacteria ferment dietary fiber.
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Elevated
Zonulin
Zonulin (technically pre-haptoglobin 2) is a protein your own gut cells secrete that controls how tightly the cells lining your intestine are bound together.
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