General Gut Dysbiosis 6-Week Recovery Protocol
Generalized dysbiosis (low diversity, no single dominant pathogen, multiple commensals depleted) is the most common pattern on a 16S sequencing test like Biomesight. It is also the hardest pattern to fix, because there is no single organism to target. This protocol works on three principles. Phase 1 removes the most common dysbiosis drivers (alcohol, ultra-processed food, chronic NSAID use, sleep deprivation) and starts fermented foods to deliver immediate microbial diversity. Phase 2 adds the 30 plants per week diversity target, which has the strongest evidence for raising overall gut diversity scores. Phase 3 establishes the long-term diet pattern that sustains diversity, plus adds longitudinal monitoring (retest in 12 weeks, then again at 6 months).
Who this protocol is for
Adults with low diversity on a Biomesight, Thorne, or ZOE microbiome test, especially when the report flags a shifted Bacteroidetes-to-Firmicutes ratio without naming a specific pathogen or single deficient marker.
What to expect, week by week
- 1 Week 1 to 2: Subtle changes. Better sleep is the most common first signal.
- 2 Week 3 to 4: Bowel regularity improves, post-meal energy increases.
- 3 Week 5 to 6: Food variety expands without symptom return.
- 4 Retest at 12 weeks. Diversity is the slowest-moving metric in functional medicine.
The 6-week food plan
Built from the protocol for Bacteroidetes/Firmicutes Ratio, the primary marker behind this condition. Phase 1 is partially visible. The full plan with exact quantities unlocks when you upload your stool test PDF.
- Target: 15 different plant species See your personalized dose
- Mixed salad greens (4+ types) See your personalized dose
Unlock the full personalized version
This is the off-the-shelf protocol for Dysbiosis recovery. Upload your stool test PDF and we will build the version that handles your specific marker pattern (most people have 4 to 7 abnormal markers, not just one), with conflicts resolved and a grocery list ready to send to Instacart or Kroger.
Upload my lab PDFThe markers behind this protocol
The primary driver is Bacteroidetes/Firmicutes Ratio. Click through for what the result means in detail. Supporting markers below often co-occur and inform the full protocol.
Common mistakes practitioners see
- Chasing a specific organism instead of fixing the diversity deficit.
- Eating the same 10 'healthy' foods every day (variety matters more than perfection).
- Ignoring lifestyle drivers (sleep, alcohol, stress) that suppress diversity directly.
- Stopping at week 6 expecting a full recovery (diversity rebuilds over months, not weeks).
When to escalate
- New severe GI symptoms appearing during the protocol.
- Suspected pathogen on a follow-up stool test (refer to functional medicine clinician).
- Persistent unexplained weight loss.
These signs mean stop the protocol and see a clinician. The protocol is not designed to manage acute or severe disease.