How to read your Genova GI-Effects results
Genova GI-Effects is one of the longest-running comprehensive stool tests in functional medicine. Where the GI-MAP focuses tightly on organisms, GI-Effects emphasizes the metabolic and digestive layer: short-chain fatty acids (butyrate, propionate, acetate), pancreatic enzyme function via Elastase-1, fecal fat absorption via Steatocrit, and inflammation via Calprotectin. It is often the better choice when the clinical question is digestive function rather than infection, or when low SCFA and butyrate are suspected.
How Genova GI-Effects works
Combined approach using PCR for organism detection plus mass spectrometry and biochemistry for short-chain fatty acids, fecal fat (steatocrit), and digestive markers. Genova's strength is the breadth of metabolic and digestive measurements, not just organism counts.
What Genova GI-Effects does well
- Direct quantification of short-chain fatty acids (butyrate, propionate, acetate)
- Strong digestive function panel (Elastase-1, Steatocrit, fecal fat)
- Combines organism detection with metabolic measurements
- Long-standing reference ranges with good clinical history
- Multiple panel tiers to match the clinical question
What Genova GI-Effects misses
- Less detailed H. pylori virulence factor panel than GI-MAP
- Smaller opportunistic-organism list than GI-MAP
- Higher cost than the lighter GI-MAP panel
- Does not include 16S diversity sequencing
What's on the Genova GI-Effects panel
These are the markers Genova GI-Effects reports on. Click any underlined marker to see what the result means and how to address it.
- Akkermansia muciniphila
- Faecalibacterium prausnitzii
- Methanobrevibacter smithii
- Bifidobacterium spp.
- Lactobacillus spp.
- Candida species
- Blastocystis hominis
- Helicobacter pylori
- Secretory IgA
- Calprotectin
- Zonulin
- Pancreatic Elastase-1
- Steatocrit / Fecal Fat
- Beta-glucuronidase
- Lactoferrin
- Total Short-Chain Fatty Acids
- Butyrate (n-Butyrate)
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Upload my Genova GI-Effects PDFWhen Genova GI-Effects is the right test
- low energy and post-meal sluggishness (SCFA workup)
- fat malabsorption (greasy stools, undigested food)
- chronic constipation with suspected low SCFA
- suspected pancreatic insufficiency
- inflammation on prior tests with no clear organism cause